-When a lytic lesion is suspected, the radiologist must keep in mind the possibility of a normal variant, such as a pseudocyst. Two common locations for pseudocysts are the humeral head and the calcaneus. The pseudocyst of the humeral head is typically located in the region of the greater tuberosity, while the pseudocyst of the calcaneus is typically located anteriorly. -Proximal humerus chondrosarcoma is a rare localization of the common primary malignant cartilaginous tumor.

Reference: 1-https://appliedradiology.com/articles/general-approach-to-lytic-bone-lesions 2-https://www.researchgate.net/figure/Proximal-humerus-lytic-lesion-with-metaphyseal-and-epiphyseal-involvement_fig1_350678996