-Lytic skull lesions have a relatively wide differential that can be narrowed, by considering if there are more than one lesion and whether the mandible is involved. -Lytic lesions of the skull include a wide range of diseases, ranging from benign conditions such as arachnoid granulations or vascular lacunae, to aggressive malignant lesions such as lymphomas or metastases.

Reference:- 1-https://radiopaedia.org/articles/lytic-skull-lesion. 2-https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206388/.